Formulation and Evaluation of gastro retentive Tablet of verapamil

This study developed and evaluated mouth disintegrating tablets (MDTs) of Empagliflozin to enhance patient compliance and rapid drug onset. Using UV spectrophotometry (λmax 225nm in 0.1NHCl), MDTs were prepared via direct compression with superdisintegrants SSG, Crospovidone, and Croscarmellose sodium. All formulations met pharmacopeial standards. Batch F-6 with Crospovidone showed the best performance, releasing 99% of the drug within 30 minutes. The findings confirm the effectiveness of a minimal-excipient, direct compression method for efficient Empagliflozin delivery.

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Publication Details

Journal
International journal of research in pharmacy and life sciences.
Published
2025-06-27
DOI
https://doi.org/10.30904/j.ijrpls.2025.4841
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
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article

Formulation and Evaluation of gastro retentive Tablet of verapamil

U Shilpa, Suresh Ch, Sai Prasanna G, Javeria Khaleel et al.
International journal of research in pharmacy and life sciences.
Drug Solubulity and Delivery Systems
article

Formulation and Evaluation of gastro retentive Tablet of verapamil

U Shilpa, Suresh Ch, Sai Prasanna G, Javeria Khaleel, N Rani, R Kaveri
article en

Abstract

This study developed and evaluated mouth disintegrating tablets (MDTs) of Empagliflozin to enhance patient compliance and rapid drug onset. Using UV spectrophotometry (λmax 225nm in 0.1NHCl), MDTs were prepared via direct compression with superdisintegrants SSG, Crospovidone, and Croscarmellose sodium. All formulations met pharmacopeial standards. Batch F-6 with Crospovidone showed the best performance, releasing 99% of the drug within 30 minutes. The findings confirm the effectiveness of a minimal-excipient, direct compression method for efficient Empagliflozin delivery.

International journal of research in pharmacy and life sciences.Vol. 13(1)
Telangana University (IN)
Openalex Percentile: Top 83%
Drug Solubulity and Delivery Systems
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