Correlation between neutrophil extracellular traps and macrophages in thrombi of patients with acute ischemic stroke

NETs are contained in the thrombus of patients with acute ischemic stroke. The numbers of M1 macrophages and M2 macrophages in thrombus are positively correlated with the content of NETs. M1 and M2 macrophages derived from human monocytes have the ability to degrade and clear NETs, and the effect of M1 macrophages in degrading and clearing NETs may be stronger than M2 macrophages.