Rotational Motion in Bispidines: A Conformational Study
A detailed conformational analysis of <i>N</i>-substituted bispidines has been performed to determine the factors governing the restricted rotational motion induced by the substituents. This investigation combines computational studies of the transition state involved in the rotation with experimental characterization of the rotamers arising from the restricted rotation.
Authors
- Valerio Fasano (ORCID: https://orcid.org/0000-0003-1819-4483)
- Andrea Citarella (ORCID: https://orcid.org/0000-0001-5881-7142)
- Daniele Passarella (ORCID: https://orcid.org/0000-0001-6180-9581)
- Leonardo Lo Presti (ORCID: https://orcid.org/0000-0001-6361-477X)
- L. Pozzi (ORCID: https://orcid.org/0009-0002-1670-6561)
- Giovanni Macetti (ORCID: https://orcid.org/0000-0001-9935-7955)
- Francesco Migliano
Institutions
- University of Milan (IT)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1021/acs.orglett.5c02839
- Primary Topic
- Molecular spectroscopy and chirality
- Type
- article
- Field-Weighted Citation Impact
- 0.00