Tracing the evolutionary dynamics of carbapenem-resistant Escherichia coli in recurrent and multi-site infections
These findings underscore the significance of bacterial genomic changes and plasmid transfer in driving phenotypic evolution, enabling CREC to adapt and persist within hosts under selective pressures, thereby sustaining infections.
Authors
- Tran Thi Dieu Thuy (ORCID: https://orcid.org/0009-0003-0020-3465)
- Pei-Yun Kuo (ORCID: https://orcid.org/0000-0002-3905-3105)
- Ching‐Hao Teng (ORCID: https://orcid.org/0000-0002-4615-094X)
- Ya-Yu Cheng
- Ya‐Min Tsai (ORCID: https://orcid.org/0000-0002-2529-8988)
- Cheng‐Yen Kao (ORCID: https://orcid.org/0000-0001-8782-3912)
- Yao‐Chi Chuang (ORCID: https://orcid.org/0000-0002-1468-3792)
- Yen-Zhen Zhang
- Yi-Hong Lee
- Ming-Cheng Wang (ORCID: https://orcid.org/0000-0003-1668-9319)
- Carl Jay Ballena Bregente (ORCID: https://orcid.org/0009-0001-5627-9608)
- Yu‐Chen Chen (ORCID: https://orcid.org/0000-0001-8434-7084)
- Yuhua Fan (ORCID: https://orcid.org/0000-0003-1261-247X)
- Donald Ming-Tak Ho
Institutions
- National Yang Ming Chiao Tung University (TW)
- Chang Gung University (TW)
- China Medical University (TW)
- Taipei Veterans General Hospital (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- En Chu Kong Hospital (TW)
- Taiwan Nurses Association (TW)
- National Cheng Kung University Hospital (TW)
- Southwestern University (PH)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s13099-025-00746-9
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Educational Development Foundation
- Ministry of Education, India
- China Medical University
- Taipei Veterans General Hospital