A comparative analysis of tumor markers reveals EDA fibronectin as a promising target in high-grade serous ovarian cancer
These findings highlight that EDA-FN is an excellent target for HGSOC, while CEA could serve as a potential target for MOC. Clinical investigations are warranted to evaluate innovative treatments in ovarian cancer targeting these antigens.
Authors
- Dario Neri (ORCID: https://orcid.org/0000-0001-5234-7370)
- Alessia Piermattei (ORCID: https://orcid.org/0000-0001-7164-4952)
- Giovanni Scambia (ORCID: https://orcid.org/0000-0002-9503-9041)
- Francesca Sillano
- Frederik Peissert (ORCID: https://orcid.org/0000-0002-1856-8118)
- Emanuele Puca (ORCID: https://orcid.org/0000-0002-2869-3203)
- Gian Franco Zannoni (ORCID: https://orcid.org/0000-0002-4473-7560)
- Louis Plüss (ORCID: https://orcid.org/0009-0003-6426-7249)
- Tina Pasciuto (ORCID: https://orcid.org/0000-0003-2959-8571)
- Antonio Travaglino (ORCID: https://orcid.org/0000-0003-4002-1618)
- R. De Luca (ORCID: https://orcid.org/0000-0001-8137-6904)
- Camilla Nero (ORCID: https://orcid.org/0000-0002-4442-4046)
- Anna Fagotti
- Marianna Buttarelli (ORCID: https://orcid.org/0000-0002-9062-8605)
- Diana Giannarelli (ORCID: https://orcid.org/0000-0002-6085-1195)
- Nicoletta D’Alessandris (ORCID: https://orcid.org/0000-0002-9580-6343)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Insubria (IT)
- Agostino Gemelli University Polyclinic (IT)
- Philogen (Italy) (IT)
- Philochem (Switzerland) (CH)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s13048-025-01772-6
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute