Exercício e tDCS na variabilidade cardiaca e nivel de cortisol na fibromialgia

Objective. To analyze and describe the effects of physical exercise combined with transcranial direct current stimulation (tDCS), applied over the left dorsolateral prefrontal cortex (DLPFC) at an intensity of 2mA, on serotonin levels, salivary cortisol, and clinical characteristics of a participant with fibromyalgia. Method. A single-subject design was conducted with an "A-B-C" protocol divided into six weeks. Protocol "A" consisted of two weeks of aerobic exercise for 30 minutes; protocol "B" included two weeks of aerobic exercise for 30 minutes combined with active tDCS during the first 20 minutes; and protocol "C" consisted of two weeks of aerobic exercise for 30 minutes combined with sham tDCS. The participant was assessed at the beginning and end of each protocol using the COMPASS 21 scale, heart rate variability, and salivary cortisol levels. Results. Protocol B showed better outcomes in autonomic nervous system modulation and salivary cortisol levels. Conclusion. The physical exercise protocol resulted in clinical differences in cortisol levels and autonomic nervous system modulation.

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Publication Details

Journal
Revista Neurociências
Published
2025-08-25
DOI
https://doi.org/10.34024/rnc.2025.v33.19713
Primary Topic
Fibromyalgia and Chronic Fatigue Syndrome Research
Type
article
Field-Weighted Citation Impact
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article

Exercício e tDCS na variabilidade cardiaca e nivel de cortisol na fibromialgia

Eduardo Henrique Loreti, Hian Wellington Santos Vasques
Revista Neurociências
Fibromyalgia and Chronic Fatigue Syndrome Research
article

Exercício e tDCS na variabilidade cardiaca e nivel de cortisol na fibromialgia

Eduardo Henrique Loreti, Hian Wellington Santos Vasques
article en

Abstract

Objective. To analyze and describe the effects of physical exercise combined with transcranial direct current stimulation (tDCS), applied over the left dorsolateral prefrontal cortex (DLPFC) at an intensity of 2mA, on serotonin levels, salivary cortisol, and clinical characteristics of a participant with fibromyalgia. Method. A single-subject design was conducted with an "A-B-C" protocol divided into six weeks. Protocol "A" consisted of two weeks of aerobic exercise for 30 minutes; protocol "B" included two weeks of aerobic exercise for 30 minutes combined with active tDCS during the first 20 minutes; and protocol "C" consisted of two weeks of aerobic exercise for 30 minutes combined with sham tDCS. The participant was assessed at the beginning and end of each protocol using the COMPASS 21 scale, heart rate variability, and salivary cortisol levels. Results. Protocol B showed better outcomes in autonomic nervous system modulation and salivary cortisol levels. Conclusion. The physical exercise protocol resulted in clinical differences in cortisol levels and autonomic nervous system modulation.

Revista NeurociênciasVol. 33
Openalex Percentile: Top 74%
Fibromyalgia and Chronic Fatigue Syndrome Research
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