A Randomized Controlled Trial of Resection Versus Thermal Ablation of Colorectal Cancer Liver Metastases (New Comet): Study Protocol
The primary endpoint is local tumor recurrence at 12 months. Secondary endpoints include overall survival, disease-free survival, time to surgical failure, health-related quality of life, complications, and cost-effectiveness (trial registration no.: NCT05129787).
Authors
- Andreas Espinoza (ORCID: https://orcid.org/0000-0002-6230-3088)
- Bård I. Røsok (ORCID: https://orcid.org/0000-0002-1358-8056)
- Sheraz Yaqub (ORCID: https://orcid.org/0000-0002-5696-2319)
- Kristoffer Lassen (ORCID: https://orcid.org/0000-0003-0039-6554)
- Egidijus Pelanis
- Karina Roheim Lappen
- Ida Torunn Bjørk (ORCID: https://orcid.org/0000-0002-3090-935X)
- Per Steinar Halvorsen (ORCID: https://orcid.org/0000-0003-3415-1184)
- Åsmund Avdem Fretland (ORCID: https://orcid.org/0000-0002-0945-5189)
- Kristoffer W. Brudvik (ORCID: https://orcid.org/0000-0002-1503-2107)
- Bjørn Edwin (ORCID: https://orcid.org/0000-0002-3137-6225)
- Daniel Østergaard
- Marit Helen Andersen (ORCID: https://orcid.org/0000-0002-6115-3268)
- Trygve Syversveen (ORCID: https://orcid.org/0000-0002-2278-5203)
- Ingrid Schrøder Hansen
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- UiT The Arctic University of Norway (NO)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1245/s10434-025-17984-5
- Citations
- 3
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.97
Funders
- Universitetet i Oslo