Urinary 3-methylhistidine as a potential biomarker for sepsis-associated acute kidney injury: multidimensional metabolomics analysis in mice and human
We proposed that urinary 3-Methylhistidine has potential diagnostic value for SA-AKI screening. Future studies will focus on its performance in other clinical populations to comprehensively evaluate its diagnostic role.
Authors
- Feiyu Luan
- Yi Bai (ORCID: https://orcid.org/0000-0002-1179-3734)
- Yang Zhou (ORCID: https://orcid.org/0000-0002-9087-0522)
- Xibo Wang (ORCID: https://orcid.org/0000-0002-4220-9246)
- Feifeng Liu (ORCID: https://orcid.org/0000-0003-4683-6973)
- Pengfei Huang (ORCID: https://orcid.org/0000-0001-5602-1730)
- Mengyao Yuan (ORCID: https://orcid.org/0000-0002-7339-689X)
- Kaijiang Yu (ORCID: https://orcid.org/0000-0001-8456-9664)
- Yinghao Luo
- Changsong Wang (ORCID: https://orcid.org/0000-0002-0079-5259)
- Jinyuan Wu (ORCID: https://orcid.org/0000-0003-4432-9521)
- Dawei Wang (ORCID: https://orcid.org/0000-0002-7868-775X)
- Tao Wu (ORCID: https://orcid.org/0000-0003-1567-1512)
- Libo Shen (ORCID: https://orcid.org/0000-0002-1957-937X)
- Xuan Wang (ORCID: https://orcid.org/0000-0002-3556-3239)
- Qianqian Zhang (ORCID: https://orcid.org/0000-0003-3442-4461)
- Yuhan Liu (ORCID: https://orcid.org/0000-0003-1990-4184)
- Yue Li (ORCID: https://orcid.org/0000-0001-6924-8969)
- Yuxin Zhang (ORCID: https://orcid.org/0000-0001-5106-4125)
- Yanqi Liu (ORCID: https://orcid.org/0000-0003-3499-0201)
- Yu Xin
- Weiting Zhang (ORCID: https://orcid.org/0000-0002-7473-2234)
- Mingyan Zhao (ORCID: https://orcid.org/0000-0003-4457-1684)
- Nan Zhang (ORCID: https://orcid.org/0000-0001-6770-3534)
Institutions
- Harbin Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang Provincial Hospital (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- Education Department of Heilongjiang Province (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01550-z
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China