Association between enlarged perivascular space ( <scp>ePVS</scp> ) density and stereo‐electroencephalography ( <scp>SEEG</scp> ) biomarkers of epileptogenicity

ePVS density may not be a consistent biomarker of SEEG-defined epileptogenicity. The relationship between reduced ePVS and epileptogenicity in MRI-negative cases warrants further study, as this may shed light on underlying pathobiology and EZ biomarkers. Different imaging techniques may be able to capture the relationship between the glymphatic system disruption and epileptogenicity.

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Publication Details

Journal
Epilepsia
Published
2025-08-26
DOI
https://doi.org/10.1111/epi.18614
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between enlarged perivascular space ( ePVS ) density and stereo‐electroencephalography ( SEEG ) biomarkers of epileptogenicity

Terence John O'Brien, Parveen Sagar, Joshua Laing, Thanomporn Wittayacharoenpong et al.
1 links
Epilepsia
Cerebrospinal fluid and hydrocephalus
article

Association between enlarged perivascular space ( ePVS ) density and stereo‐electroencephalography ( SEEG ) biomarkers of epileptogenicity

Terence John O'Brien, Parveen Sagar, Joshua Laing, Thanomporn Wittayacharoenpong, Meng Law, Matthew Gutman, William Pham, Benjamin Sinclair, Patrick Kwan, Jacob Bunyamin, Andrew Neal, Noam Bosak, Zhibin Chen, Martin Hunn
article en

Abstract

ePVS density may not be a consistent biomarker of SEEG-defined epileptogenicity. The relationship between reduced ePVS and epileptogenicity in MRI-negative cases warrants further study, as this may shed light on underlying pathobiology and EZ biomarkers. Different imaging techniques may be able to capture the relationship between the glymphatic system disruption and epileptogenicity.

EpilepsiaVol. 66(12)
Alfred Health (AU), Monash University (AU)
Monash University
Openalex Percentile: Top 76%
Cerebrospinal fluid and hydrocephalus
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Association between enlarged perivascular space ( <scp>ePVS</scp> ) density and stereo‐electroencephalography ( <scp>SEEG</scp> ) biomarkers of epileptogenicity — Terence John O'Brien, Parveen Sagar, et al. · Epilepsia (2025) | TGRS Research Map | TGRS