CardioLike-Net: An edge-end inter-patient arrhythmia classifier with quantization-aware-training for wearable ECG applications
Wearable electrocardiogram monitors equipped with edge-end classifier is a transformative tool for managing cardiovascular diseases. Whereas, electrocardiogram pattern variations have posed difficulties in obtaining robust accuracy among different individuals. To address this issue, this paper proposes a novel neural network architecture, resembling the diagnosis procedure of cardiologists while utilizing the robustness of artificial intelligent models. Also, this work introduces a quantization-aware-training algorithm that enables weight and activation quantization within recurrent neural network layers, which has traditionally been difficult due to their temporal dependencies and complex internal structure. Evaluated on a widely used public electrocardiogram dataset, it shows over 96.4% inter-patient classification accuracy across 43 subjects, which is superior to other state-of-the-arts. The quantized model maintains accuracy with only a 0.1% loss while reducing model precision to 4-bit integer weights and 6-bit integer activations. When deployed on a field-programmable gate array, the proposed classifier consumes 24 mW at a maximum clock frequency of 40MHz with a latency of 420ms. Compared to the full-precision counterpart, the hardware resource usage is significantly reduced, including reductions of 47.2% in look up tables, 45.5% in flip-flops, 78.9% in block memories, and 93.0% in digital signal processors. The source code is available at https://github.com/xinziXu/CardioLike-Net.git . • Architecture: This work introduces a CardioLike-Net architecture, inspired by the diagnostic process of cardiologists, reducing feature redundancy and the adverse impact of electrocardiogram signal variations. • Quantization: A novel quantization-aware-training algorithm is proposed to quantize the recurrent neural network layers to low-bit while maintain high accuracy. • Implementation: An edge-end arrhythmia classifier with high inter-patient accuracy and low hardware resources is achieved.
Authors
- Yang Zhao (ORCID: https://orcid.org/0000-0002-2236-6092)
- Yanxing Suo (ORCID: https://orcid.org/0000-0002-0307-609X)
- Qinyu Chen (ORCID: https://orcid.org/0009-0005-9480-6164)
- Qiao Cai (ORCID: https://orcid.org/0000-0003-2662-7066)
- Chang Gao (ORCID: https://orcid.org/0000-0002-3284-4078)
- Guoxing Wang (ORCID: https://orcid.org/0000-0002-0235-1475)
- Xinzi Xu (ORCID: https://orcid.org/0000-0001-5869-1631)
- Yunfang Zhang (ORCID: https://orcid.org/0000-0002-3687-2770)
Institutions
- SIB Swiss Institute of Bioinformatics (CH)
- Shanghai Jiao Tong University (CN)
- University of Zurich (CH)
Publication Details
- Journal
- Biomedical Signal Processing and Control
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1016/j.bspc.2025.108604
- Citations
- 1
- Primary Topic
- ECG Monitoring and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Key Technologies Research and Development Program
- National Key Research and Development Program of China