An Alternative Method for the Efficient Synthesis of Aminoindane‐Based Chiral Triazolium Salts

Abstract A list of functionalized aminoindane‐based chiral triazolium salts has been prepared from readily available 1‐amino‐2‐indanol via a new method in the presence of Im 2 CS, H 2 O 2 , and HBF 4 . Over the years, Rovis, Bode, Suzuki, and Scheidt et al. developed a method for preparing chiral thiazolium salts using Meerwein's reagent (Me 3 OBF 4 ) arylhydrazine, and excess amounts of (EtO) 3 CH as key reagent and the reaction proceeded at high temperature. We report alternative methods to access chiral triazolium salts with better yields (67%–87%), clean reaction, mild reaction conditions and ambient temperature, operational simplicity, a simple purification process, and tolerating a wide range of functional groups.