Low bacterial metabolism as a central mechanism of antimicrobial resistance and potential therapeutic target of staphylococcal biofilms in ventricular assist device driveline infections
This study identified repressed bacterial metabolism as a central mechanism underpinning biofilm AMR and provided an effective therapeutic target for biofilm-associated driveline infections.
Authors
- Tieli Zhou (ORCID: https://orcid.org/0000-0002-2171-4710)
- Liumei Ye
- To Nguyen Thi Nguyen
- Francesca L. Short (ORCID: https://orcid.org/0000-0002-0025-4858)
- David C. McGiffin
- Yue Qu (ORCID: https://orcid.org/0000-0002-4683-708X)
- Xenia Kostoulias (ORCID: https://orcid.org/0000-0002-8611-2198)
- Anton Y. Peleg (ORCID: https://orcid.org/0000-0002-2296-2126)
- Yao Sun (ORCID: https://orcid.org/0000-0002-9826-1756)
Institutions
- Wenzhou Medical University (CN)
- Discovery Institute (US)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- The Alfred Hospital (AU)
- Ambulance Victoria (AU)
- Monash Alfred Psychiatry Research centre (AU)
- Monash University (AU)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-08-13
- DOI
- https://doi.org/10.1093/jac/dkaf316
- Citations
- 2
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Monash University