Randomized clinical trial comparing removal followed by topical imiquimod versus removal followed by topical methylprednisolone in the treatment of keloids

Surgical removal plus application of topical imiquimod was shown as safe, and its efficacy was not statistically inferior for the treatment of keloids as compared to methylprednisolone. Due to the lack of efficacy in most therapeutic modalities, surgical removal plus topical imiquimod could be recommended as an additional first line therapy and especially for recurrent keloids. Studies with larger samples are necessary to evaluatre therapies for keloids.

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Institutions

Publication Details

Journal
Acta Cirúrgica Brasileira
Published
2025-01-01
DOI
https://doi.org/10.1590/acb406225
Citations
3
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
6.01
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article

Randomized clinical trial comparing removal followed by topical imiquimod versus removal followed by topical methylprednisolone in the treatment of keloids

Márcio F. Chedid, Rafaela Kathrine Silva, Claudia Elizabeth Thompson, Mônica Manela‐Azulay et al.
3 citations
Acta Cirúrgica Brasileira
Dermatologic Treatments and Research
6.01
article

Randomized clinical trial comparing removal followed by topical imiquimod versus removal followed by topical methylprednisolone in the treatment of keloids

Márcio F. Chedid, Rafaela Kathrine Silva, Claudia Elizabeth Thompson, Mônica Manela‐Azulay, Andrea Ricciardi, David Rubem Azulay
article en
3 citations

Abstract

Surgical removal plus application of topical imiquimod was shown as safe, and its efficacy was not statistically inferior for the treatment of keloids as compared to methylprednisolone. Due to the lack of efficacy in most therapeutic modalities, surgical removal plus topical imiquimod could be recommended as an additional first line therapy and especially for recurrent keloids. Studies with larger samples are necessary to evaluatre therapies for keloids.

Acta Cirúrgica BrasileiraVol. 40
Universidade Federal do Rio de Janeiro (BR), Universidade Federal do Rio Grande do Sul (BR), Universidade Federal de Ciências da Saúde de Porto Alegre (BR), Hospital de Clínicas de Porto Alegre (BR), Hospital Nossa Senhora da Conceição (BR)
Openalex Percentile: Top 4%
Dermatologic Treatments and Research
6.01
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Randomized clinical trial comparing removal followed by topical imiquimod versus removal followed by topical methylprednisolone in the treatment of keloids — Márcio F. Chedid, Rafaela Kathrine Silva, et al. · Acta Cirúrgica Brasileira (2025) | TGRS Research Map | TGRS