Interleukin-22 and interleukin-22 binding protein signaling axis influences intubation status in trauma

Interleukin-22 may serve as a biomarker for trauma-induced respiratory failure, with lower levels associated with greater injury severity and the need for intubation. Further studies are needed to explore its potential as a therapeutic and to better understand its role in trauma care.

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Publication Details

Journal
Surgery
Published
2025-08-25
DOI
https://doi.org/10.1016/j.surg.2025.109608
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

Interleukin-22 and interleukin-22 binding protein signaling axis influences intubation status in trauma

Danielle Tatum, Derek A. Pociask, Aaron L. Albuck, M. Shenk et al.
Surgery
Respiratory Support and Mechanisms
article

Interleukin-22 and interleukin-22 binding protein signaling axis influences intubation status in trauma

Danielle Tatum, Derek A. Pociask, Aaron L. Albuck, M. Shenk, Jacob Broome, Sharven Taghavi, Juan Duchesne, Alison Smith, Jay K. Kolls, Christine M. Bojanowski, Valeria Noguera, Olan Jackson‐Weaver, Augustus Anderson, Wid Covey
article en

Abstract

Interleukin-22 may serve as a biomarker for trauma-induced respiratory failure, with lower levels associated with greater injury severity and the need for intubation. Further studies are needed to explore its potential as a therapeutic and to better understand its role in trauma care.

SurgeryVol. 187
Tulane University (US), Louisiana State University Health Sciences Center New Orleans (US)
American Heart Association
Zero hunger
Openalex Percentile: Top 67%
Respiratory Support and Mechanisms
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Interleukin-22 and interleukin-22 binding protein signaling axis influences intubation status in trauma — Danielle Tatum, Derek A. Pociask, et al. · Surgery (2025) | TGRS Research Map | TGRS