Cyclodextrin-based nanosponge co-delivery of doxorubicin and EMD: synergistic anticancer activity with improved selectivity toward cancer cells
Nanosponges, exploiting hydrophilic and hydrophobic sites, were co-loaded with doxorubicin and EMD, resulting in a synergistic apoptotic effect in cancer cells, not observed for free co-delivery or separate encapsulation of the two drugs.
Authors
- Paolo di Gianvincenzo
- Pithi Chanvorachote (ORCID: https://orcid.org/0000-0002-3103-3249)
- Sergio Moya (ORCID: https://orcid.org/0000-0002-7174-1960)
- Chanchai Boonla (ORCID: https://orcid.org/0000-0002-6515-4321)
- Marco D’Abramo (ORCID: https://orcid.org/0000-0001-6020-8581)
- Desirè Di Silvio (ORCID: https://orcid.org/0000-0002-7852-1055)
- Ariadna María Birocco
- Sunissa Thongsom
- Giulia Ciattaglia
- Ahmed Subrati
Institutions
- Chulalongkorn University (TH)
- Universidad de Buenos Aires (AR)
- CIC biomaGUNE (ES)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- RSC Pharmaceutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5pm00183h
- Citations
- 2
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- Ministerio de Ciencia e Innovación
- Agencia Estatal de Investigación