Skin Biopsy Diagnosis of Late-Onset Psychosis as Prodromal Dementia With Lewy Bodies: A Case Series

DLB may underlie a substantial proportion of late-onset psychosis. Clinically available biomarker tests, routinely used in neurology to diagnose DLB and other neurodegenerative disorders with motor or cognitive symptoms, can also identify these disorders when they begin with psychiatric symptoms. Prospective biomarker-based research is essential to improve recognition of psychiatric-onset DLB, refine diagnostic criteria, and guide appropriate treatment.