Isolation of a SARS-CoV-2 strain from pediatric patients in South Korea: biologic and genetic characterization
The pediatric N15 isolate represents a unique 19B lineage virus, retaining ancestral genomic features while harboring rare mutations. Its efficient replication and drug sensitivity underscore its value as a reference strain for comparative studies against circulating variants and for evaluating antiviral efficacy.
Authors
- Jae Myun Lee (ORCID: https://orcid.org/0000-0002-5273-3113)
- Hee‐Chun Chung (ORCID: https://orcid.org/0000-0003-4666-5393)
- Su Jin Hwang (ORCID: https://orcid.org/0000-0001-9182-8281)
- Jun-Yeop Shim
- Van Giap Nguyen (ORCID: https://orcid.org/0000-0001-5250-1825)
- Si Hwan Ko (ORCID: https://orcid.org/0009-0005-3739-4597)
- Hyeon Woo Chung
- Sung Hoon Park (ORCID: https://orcid.org/0000-0001-5683-9882)
- Sung Jae Kim (ORCID: https://orcid.org/0000-0002-8813-012X)
- Kyoung‐Min Park
- Dong il Park
Institutions
- Yonsei University (KR)
- Vietnam National University of Agriculture (VN)
- Hansol Chemical (South Korea) (KR)
- Kyungbok University (KR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3389/fmicb.2025.1654224
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation of Korea
- Korea Science and Engineering Foundation