Recognizing pediatric febrile myoclonus: a video-documented case report and review of the current literature

Febrile myoclonus (FM) is a benign condition characterized by the sudden onset of generalized, multifocal, or segmental jerks during fever, without signs of central nervous system infections, resolving as the temperature elevation subsides. This condition is poorly described in literature, and its incidence is not well identified. We present the case of a 1-year-old child who developed myoclonic jerks during a febrile episode, diagnosed with FM. The child exhibited a normal neurological examination and neuromotor development appropriate for age. The electroencephalogram (EEG) showed no epileptiform discharges during the events, and past medical or familiar history was negative for epilepsy or any other neurological condition. We conducted a narrative review of the current literature to improve understanding of this benign clinical manifestation. Additionally, we included audio and video material to aid physicians in recognizing the condition, avoiding unnecessary diagnostic procedures and overtreatment with antiseizure medications. Our goal is to increase awareness of this rare phenomenon and expand its phenotypical spectrum.

Authors

Institutions

Publication Details

Journal
Frontiers in Pediatrics
Published
2025-08-26
DOI
https://doi.org/10.3389/fped.2025.1653744
Primary Topic
Glycogen Storage Diseases and Myoclonus
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Recognizing pediatric febrile myoclonus: a video-documented case report and review of the current literature

Michele Minerva, Federica Lotti, Salvatore Grosso, Maria Rosaria Curcio et al.
Frontiers in Pediatrics
Glycogen Storage Diseases and Myoclonus
article

Recognizing pediatric febrile myoclonus: a video-documented case report and review of the current literature

Michele Minerva, Federica Lotti, Salvatore Grosso, Maria Rosaria Curcio, L. Perilli, A. Francioni
article en

Abstract

Febrile myoclonus (FM) is a benign condition characterized by the sudden onset of generalized, multifocal, or segmental jerks during fever, without signs of central nervous system infections, resolving as the temperature elevation subsides. This condition is poorly described in literature, and its incidence is not well identified. We present the case of a 1-year-old child who developed myoclonic jerks during a febrile episode, diagnosed with FM. The child exhibited a normal neurological examination and neuromotor development appropriate for age. The electroencephalogram (EEG) showed no epileptiform discharges during the events, and past medical or familiar history was negative for epilepsy or any other neurological condition. We conducted a narrative review of the current literature to improve understanding of this benign clinical manifestation. Additionally, we included audio and video material to aid physicians in recognizing the condition, avoiding unnecessary diagnostic procedures and overtreatment with antiseizure medications. Our goal is to increase awareness of this rare phenomenon and expand its phenotypical spectrum.

Frontiers in PediatricsVol. 13
Azienda Ospedaliera Universitaria Senese (IT)
Openalex Percentile: Top 66%
Glycogen Storage Diseases and Myoclonus
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Recognizing pediatric febrile myoclonus: a video-documented case report and review of the current literature — Michele Minerva, Federica Lotti, et al. · Frontiers in Pediatrics (2025) | TGRS Research Map | TGRS