Hypokalemic Paralysis Is Not Always Periodic: A Case Series

Potassium is vital for cellular function, particularly in excitable tissues like nerves and muscles, which rely on potassium gradients to function normally. Hypokalemia can lead to severe issues such as muscle weakness and irregular heart rhythms. This case series presents four instances of hypokalemic paralysis, a neuromuscular condition that can be either periodic or isolated. The cases vary in presentation and treatment approach, highlighting the need to differentiate between primary and secondary causes of hypokalemia for optimal management. Fast and accurate diagnosis through laboratory tests and history taking is critical, and while acute management is standard, preventive strategies depend on the underlying cause. Further research is needed to establish definitive guidelines for the prevention of hypokalemic paralysis.

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Publication Details

Journal
Case Reports in Medicine
Published
2025-01-01
DOI
https://doi.org/10.1155/carm/9925534
Citations
1
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.81
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Hypokalemic Paralysis Is Not Always Periodic: A Case Series

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Case Reports in Medicine
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article

Hypokalemic Paralysis Is Not Always Periodic: A Case Series

Gaurav Mehta, Apurva Patel, Mohak Jain, Minal Shastri, Shifa Karatela, Ajay Parmar, Vidhi Gandhi, Sahaj Patel
article en
1 citations

Abstract

Potassium is vital for cellular function, particularly in excitable tissues like nerves and muscles, which rely on potassium gradients to function normally. Hypokalemia can lead to severe issues such as muscle weakness and irregular heart rhythms. This case series presents four instances of hypokalemic paralysis, a neuromuscular condition that can be either periodic or isolated. The cases vary in presentation and treatment approach, highlighting the need to differentiate between primary and secondary causes of hypokalemia for optimal management. Fast and accurate diagnosis through laboratory tests and history taking is critical, and while acute management is standard, preventive strategies depend on the underlying cause. Further research is needed to establish definitive guidelines for the prevention of hypokalemic paralysis.

Case Reports in MedicineVol. 2025(1)
Sir Sayajirao General Hospital Medical College (IN)
Openalex Percentile: Top 24%
Ion channel regulation and function
0.81
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Hypokalemic Paralysis Is Not Always Periodic: A Case Series — Gaurav Mehta, Apurva Patel, et al. · Case Reports in Medicine (2025) | TGRS Research Map | TGRS