Case Report: complete response to preoperative ipilimumab and nivolumab combination therapy in advanced papillary renal cell carcinoma with inferior vena cava tumor thrombus and multiple metastases
This case highlights the potential efficacy of preoperative combination therapy with ipilimumab and nivolumab in advanced pRCC with IVC tumor thrombus and distant metastases. The treatment achieved a complete response and allowed successful surgical resection, suggesting its potential as a viable option in similar cases.
Authors
- Toshio Takagi (ORCID: https://orcid.org/0000-0003-1775-0943)
- Yuki Kobari (ORCID: https://orcid.org/0000-0002-1407-2588)
- Shinsuke Mizoguchi (ORCID: https://orcid.org/0000-0002-0498-4495)
- Shinichi Nozaki (ORCID: https://orcid.org/0009-0000-7645-8286)
- Kazuhiko Yoshida (ORCID: https://orcid.org/0000-0002-3834-0153)
- Yoji Nagashima (ORCID: https://orcid.org/0000-0001-6691-7346)
- Chika Nagahisa
- Junpei Iizuka
- Hideki Ishida
- Hironori Fukuda
Institutions
- Tokyo Women's Medical University (JP)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3389/fonc.2025.1547387
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tokyo Women's Medical University