Efficacy of single vs. multiple botulinum toxin type A injections for trigeminal neuralgia

In summary, BTX-A treatment was effective in TN. Elderly patients and patients with good response to the first treatment were more likely to choose to continue BTX-A multiple-treatments. BTX-A remains effective within a group of TN patients who have chosen to continue BTX-A therapy, but the efficacy decreases to a certain extent after multiple treatments.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-08-26
DOI
https://doi.org/10.3389/fneur.2025.1570447
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of single vs. multiple botulinum toxin type A injections for trigeminal neuralgia

H Q Chen, Shu-yang Ma, Weifeng Luo, Yingying Xu et al.
Frontiers in Neurology
Botulinum Toxin and Related Neurological Disorders
article

Efficacy of single vs. multiple botulinum toxin type A injections for trigeminal neuralgia

H Q Chen, Shu-yang Ma, Weifeng Luo, Yingying Xu, Qilin Zhang, Ying Li, Jing Liu, Jiaxing Bao, Cean Guo
article en

Abstract

In summary, BTX-A treatment was effective in TN. Elderly patients and patients with good response to the first treatment were more likely to choose to continue BTX-A multiple-treatments. BTX-A remains effective within a group of TN patients who have chosen to continue BTX-A therapy, but the efficacy decreases to a certain extent after multiple treatments.

Frontiers in NeurologyVol. 16
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN)
National Natural Science Foundation of China, Suzhou Municipal Science and Technology Bureau
Openalex Percentile: Top 68%
Botulinum Toxin and Related Neurological Disorders
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