Enzymatic cottonseed protein alleviates DSS-induced enteritis in juvenile yellow catfish (Pelteobagrus fulvidraco): focus on macrophage polarization and necroptosis in the intestine
Our results demonstrated that ECP can alleviate DSS-induced enteritis by regulating macrophage polarization and reducing necroptosis. Furthermore, ECP supplementation effectively counteracted the exacerbation of enteritis caused by dietary protein reduction. These findings highlighted the effectiveness and feasibility of ECP in alleviating enteritis and saving protein.
Authors
- Pei Wu (ORCID: https://orcid.org/0000-0002-5530-9633)
- Xiao‐Wan Jin
- Xiao‐Qiu Zhou (ORCID: https://orcid.org/0000-0001-5266-0041)
- Guangju Zhang (ORCID: https://orcid.org/0000-0003-3607-1567)
- Weiwei Xiao (ORCID: https://orcid.org/0000-0001-5322-7055)
- Yao-Bin Ma (ORCID: https://orcid.org/0000-0003-3344-4719)
- Ya Li (ORCID: https://orcid.org/0000-0002-7710-5770)
- Lin Feng (ORCID: https://orcid.org/0009-0008-7721-226X)
- Hongmei Ren
- Wei‐Dan Jiang
- Yang Liu (ORCID: https://orcid.org/0000-0002-7240-1546)
Institutions
- Sichuan Agricultural University (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s40104-025-01248-z
- Citations
- 2
- Primary Topic
- Aquaculture disease management and microbiota
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Natural Science Foundation of China
- National Science Fund for Distinguished Young Scholars
- Modern Agricultural Technology Industry System of Shandong province