Targeting ANT1 to regulate PINK1/Parkin-mediated mitophagy is an effective treatment of trauma-induced tendon heterotopic ossification
This study identifies ANT1 as a therapeutic target and supports elamipretide as a promising treatment strategy for HO.
Authors
- Kairui Zhang (ORCID: https://orcid.org/0000-0002-8109-6598)
- Xiao Deng (ORCID: https://orcid.org/0000-0002-9006-2322)
- Guanzhi Li (ORCID: https://orcid.org/0000-0001-5366-348X)
- Li Tong (ORCID: https://orcid.org/0000-0001-9978-7517)
- Bin Yu (ORCID: https://orcid.org/0000-0002-3109-2062)
- Chao Chen (ORCID: https://orcid.org/0000-0002-3191-0838)
- Ye Deng (ORCID: https://orcid.org/0009-0008-0450-3971)
Institutions
- Nanfang Hospital (CN)
- Chengdu Second People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1016/j.jot.2025.08.002
- Primary Topic
- Heterotopic Ossification and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00