AZD5153 enhances the chemo-sensitivity of gemcitabine on pancreatic cancer cells in vitro and in vivo
In conclusion, these results suggested that AZD5153 might be an excellent GEM sensitizer in pancreatic cancer.
Authors
- Yuyu Huang (ORCID: https://orcid.org/0000-0002-5589-5417)
- Haitao Zhu (ORCID: https://orcid.org/0000-0002-4168-4053)
- Rong Dong (ORCID: https://orcid.org/0000-0003-2372-9833)
- Minmin Shen (ORCID: https://orcid.org/0000-0002-3634-0897)
- Jiang Lou (ORCID: https://orcid.org/0000-0002-2927-9709)
- Biqin Tan (ORCID: https://orcid.org/0000-0002-2286-4489)
- Youyou Yan (ORCID: https://orcid.org/0000-0002-5582-2373)
- Lulin Zhu
- Ying Li (ORCID: https://orcid.org/0000-0001-7554-0958)
- Bo Zhang (ORCID: https://orcid.org/0000-0003-2962-5314)
- Ruoqi Wang (ORCID: https://orcid.org/0009-0005-6989-1926)
- Nengming Lin (ORCID: https://orcid.org/0000-0001-8392-3588)
- Yiqian Zhu
Institutions
- Zhejiang Chinese Medical University (CN)
- Westlake University (CN)
- Tongde Hospital of Zhejiang Province (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Huzhou Central Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s12935-025-03952-2
- Citations
- 2
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province