Correlation between umbilical cord concentration of the growth hormone‐IGF axis and small for gestational age: A single‐center retrospective, observational study

Levels of IGF-1 and GH in the GH-IGF system are associated with SGA. Elevated GH levels and decreased IGF-1 levels both increase the incidence of SGA. Imbalance in the GH-IGF-1 axis may restrict fetal growth and development, thereby increasing the risk of future metabolic diseases.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2025-08-25
DOI
https://doi.org/10.1002/ijgo.70464
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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article

Correlation between umbilical cord concentration of the growth hormone‐IGF axis and small for gestational age: A single‐center retrospective, observational study

Jing Wen, Yan Zhao, Ruoling Xian, Xin Fan
International Journal of Gynecology & Obstetrics
Growth Hormone and Insulin-like Growth Factors
article

Correlation between umbilical cord concentration of the growth hormone‐IGF axis and small for gestational age: A single‐center retrospective, observational study

Jing Wen, Yan Zhao, Ruoling Xian, Xin Fan
article en

Abstract

Levels of IGF-1 and GH in the GH-IGF system are associated with SGA. Elevated GH levels and decreased IGF-1 levels both increase the incidence of SGA. Imbalance in the GH-IGF-1 axis may restrict fetal growth and development, thereby increasing the risk of future metabolic diseases.

International Journal of Gynecology & ObstetricsVol. 172(3)
Chongqing Maternal and Child Health Hospital (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 70%
Growth Hormone and Insulin-like Growth Factors
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