Urinary exosomal RAB11A serves as a novel non-invasive biomarker for diagnosis, treatment response monitoring, and prognosis in small cell lung cancer
Urinary exosomal RAB11A shows promise as a non-invasive biomarker for SCLC diagnosis, treatment response monitoring, and early detection of relapse, potentially improving clinical management of SCLC patients. The findings provide insights into SCLC pathogenesis and offer a non-invasive approach for patient monitoring, which could improve clinical management strategies.
Authors
- Chunkai Yu
- Lei Pan
- Weiwei Wang (ORCID: https://orcid.org/0000-0001-8698-4474)
- Man Zhang (ORCID: https://orcid.org/0000-0001-5166-6804)
- Na Liu (ORCID: https://orcid.org/0000-0003-3832-5591)
- Shanshan Wang (ORCID: https://orcid.org/0000-0002-1102-0483)
Institutions
- Capital Medical University (CN)
- Beijing Shijitan Hospital (CN)
Publication Details
- Journal
- Clinical Proteomics
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12014-025-09554-4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics