Comparison of biparameter and multiparameter MRI in detection of clinically significant prostate cancer across PSA stratifications
While mpMRI and bpMRI exhibit comparable overall diagnostic performance but context-dependent strengths: mpMRI demonstrates higher specificity for avoiding unnecessary biopsies when PSA ≤ 10 ng/ml, whereas bpMRI (particularly S-PI-RADS) maximizes sensitivity for csPCa detection when PSA > 10 ng/ml. LV is anticipated to serve as a complementary radiological biomarker at the absence of DCE.
Authors
- Yitao Liu (ORCID: https://orcid.org/0000-0002-0604-9601)
- Lei Shi (ORCID: https://orcid.org/0000-0001-9100-897X)
- Zhenwei Ding
- Xu Wang (ORCID: https://orcid.org/0000-0002-9230-5754)
- Liqin Yang
- Pengfei Jin (ORCID: https://orcid.org/0000-0002-9461-0453)
- Kai Li (ORCID: https://orcid.org/0000-0003-0608-4105)
- Ge Song (ORCID: https://orcid.org/0009-0001-8359-7687)
- Fawei Huang
Institutions
- Zhejiang Chinese Medical University (CN)
- Chinese Academy of Sciences (CN)
- Wuhu Fourth People Hospital (CN)
- Zhejiang Cancer Hospital (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Xian Yang Central Hospital (CN)
- Honghu Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Medical Imaging
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1186/s12880-025-01884-x
- Citations
- 2
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Natural Science Foundation of Zhejiang Province
- Science and Technology Program of Zhejiang Province