Correlation of Vitamin D with Severity of Coronary Artery Disease and Short Term Outcome in Female Versus Male Patients with Coronary Artery Disease

Background: Coronary artery disease (CAD) is a worldwide health concern. Cardiovascular disease (CAD) continues to be the predominant cause of mortality and morbidity, despite the enhancement of the current preventive and therapeutic strategies. This study aimed to correlate between vitamin D (Vit D), CAD severity and short-term outcome in females versus males with CAD. Methods: This cross-sectional study was carried out on 200 cases who were categorized into 2 equal groups: group A (males) and group B (females). Vit D level was evaluated in all the studied cases, and they also underwent electrocardiography, coronary angiography and calculation of Syntax. Results: There was a significant negative correlation between Syntax score and Vit D level, meanwhile there was a significant positive correlation between Syntax score and number of affected vessels. Conclusion: There is an association between Vit D and CAD as it can predict the CAD severity at cutoff value of ≤ 20 ng/ml, with 98.86% sensitivity, 84.82% specificity, 83.7% PPV and 99.0% NPV.