Analysis of Left Ventricular Function by Dual Source MDCT in patient with Ischemic Heart Disease In Comparison With ECHO

Purpose: To evaluate left ventricular function in patients with ischemic heart disease (IHD) by dual source CT (DSCT) in comparison to Echocardiography (ECHO). Material and Methods: This cross-sectional comparative study included 60 cases who were examined by echocardiography. They underwent DSCT coronary angiography followed by left ventricle global and regional segmental functions evaluation by two experienced radiologists with ten years of experience in cardiac imaging. We used the Pearson correlation test to estimate the correlation between the functional parameters of DSCT and ECHO. Moreover, we assessed the agreement between the functional parameters and regional wall motion abnormality (RWMA) using Altman bland test and Fleiss Kappa tests, respectively. Results: Mean left ventricular ejection fraction (LVEF), end diastolic volume (EDV), end systolic volume (ESV) and stroke volume (SV) were 53.21%, 181.52 ml, 85.99 ml and 95.22 ml, respectively on DSCT and 53.79 %, 171.15 ml, 82.3 ml and 93.55 ml respectively in ECHO with statistically significant positive correlation (r=0.98, 0,99, 0,96 and 0.99 / p < 0.001) respectively. Using a Bland-Altman analysis, EF was slightly underestimated in DSCT compared to ECHO, while both EDV and ESV were slightly overestimated in DSCT but with statistically non-significant differences between both techniques. However, regarding RWMA, by using binary scoring, there was good agreement between both modalities (K=0.86 and p < 0.001). Conclusions: DSCT can be an alternative option to ECHO in LV function assessment in patients with IHD with strong positive correlation between both techniques.