False-positive cardiac troponin I values due to macrotroponin in healthy athletes after COVID-19
Post-COVID-19, nearly half of athletes showed elevated cTnI levels due to interference from macrotroponin. Awareness among physicians and laboratorians of this analytical confounder can avoid unnecessary invasive or costly diagnostic tests in athletes with false-positive cTnI levels after COVID-19.
Authors
- Ola Hammarsten (ORCID: https://orcid.org/0000-0002-0772-6934)
- Robert Manka (ORCID: https://orcid.org/0000-0002-3383-4998)
- Peter Neyer (ORCID: https://orcid.org/0000-0002-8682-9578)
- Saara Wittfooth (ORCID: https://orcid.org/0000-0002-7886-3477)
- A Sanzone
- Luca Bernasconi (ORCID: https://orcid.org/0000-0001-6647-6448)
- Patrik Noack
- Angelika Hammerer‐Lercher (ORCID: https://orcid.org/0000-0002-9762-827X)
- Daniëlle Hof
- Christine K. Kissel (ORCID: https://orcid.org/0000-0001-5814-9121)
- Helea Junes
- Christian Müller (ORCID: https://orcid.org/0000-0002-1120-6405)
- Emel Hatun Aytaç Kaplan (ORCID: https://orcid.org/0000-0002-8385-4049)
- Gabrielle Huré
Institutions
- University of Bern (CH)
- Union Bank of Switzerland (CH)
- University of Turku (FI)
- Sahlgrenska University Hospital (SE)
- University Hospital of Basel (CH)
- Kantonsschule Stadelhofen (CH)
- University Hospital of Zurich (CH)
- Turku Centre for Biotechnology (FI)
- Kantonsspital Aarau (CH)
- Olympic Medical Center (US)
- University of Gothenburg (SE)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1515/cclm-2025-0427
- Citations
- 1
- Primary Topic
- Cardiovascular Effects of Exercise
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Northwestern University
- Universität Basel
- Universitätsspital Basel
- Riksförbundet HjärtLung
- Cancerfonden
- Sydäntutkimussäätiö
- Forschungsrat des Kantonsspitals Aarau