Prevalence and Associated Factors of Hepatic Steatosis in Patients with Type-2 Diabetes Mellitus: A Real-World Experience From a Private Healthcare Facility of South Punjab, Pakistan

1,2 individuals with T2DM.HS forms part of the broader spectrum of "non-alcoholic fatty liver diseases (NAFLD)", which can progress to more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and even 3 hepatocellular carcinoma.The link between T2DM and HS is underpinned by shared metabolic dysfunctions, including insulin 4 resistance, dyslipidemia, and obesity.In T2DM patients, chronic hyperglycemia and impaired insulin signaling lead to increased free fatty acid uptake and 5 lipid accumulation in hepatocytes.Data indicate that T2DM nearly doubles the risk of developing NAFLD, underscoring the importance of hepatic 6 health in diabetic management.With rising T2DM

Publication Details

Journal
Journal of Pakistan Society of Internal Medicine.
Published
2025-08-25
DOI
https://doi.org/10.70302/jpsim.v6i3.2552
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Prevalence and Associated Factors of Hepatic Steatosis in Patients with Type-2 Diabetes Mellitus: A Real-World Experience From a Private Healthcare Facility of South Punjab, Pakistan

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Journal of Pakistan Society of Internal Medicine.
Liver Disease Diagnosis and Treatment
article

Prevalence and Associated Factors of Hepatic Steatosis in Patients with Type-2 Diabetes Mellitus: A Real-World Experience From a Private Healthcare Facility of South Punjab, Pakistan

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Abstract

1,2 individuals with T2DM.HS forms part of the broader spectrum of "non-alcoholic fatty liver diseases (NAFLD)", which can progress to more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and even 3 hepatocellular carcinoma.The link between T2DM and HS is underpinned by shared metabolic dysfunctions, including insulin 4 resistance, dyslipidemia, and obesity.In T2DM patients, chronic hyperglycemia and impaired insulin signaling lead to increased free fatty acid uptake and 5 lipid accumulation in hepatocytes.Data indicate that T2DM nearly doubles the risk of developing NAFLD, underscoring the importance of hepatic 6 health in diabetic management.With rising T2DM

Journal of Pakistan Society of Internal Medicine.Vol. 6(3)
Openalex Percentile: Top 70%
Liver Disease Diagnosis and Treatment
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