Prevalence and Associated Factors of Hepatic Steatosis in Patients with Type-2 Diabetes Mellitus: A Real-World Experience From a Private Healthcare Facility of South Punjab, Pakistan
1,2 individuals with T2DM.HS forms part of the broader spectrum of "non-alcoholic fatty liver diseases (NAFLD)", which can progress to more severe conditions such as non-alcoholic steatohepatitis (NASH), cirrhosis, and even 3 hepatocellular carcinoma.The link between T2DM and HS is underpinned by shared metabolic dysfunctions, including insulin 4 resistance, dyslipidemia, and obesity.In T2DM patients, chronic hyperglycemia and impaired insulin signaling lead to increased free fatty acid uptake and 5 lipid accumulation in hepatocytes.Data indicate that T2DM nearly doubles the risk of developing NAFLD, underscoring the importance of hepatic 6 health in diabetic management.With rising T2DM
Publication Details
- Journal
- Journal of Pakistan Society of Internal Medicine.
- Published
- 2025-08-25
- DOI
- https://doi.org/10.70302/jpsim.v6i3.2552
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00