Prevalence of Adverse Donor Reactions among Healthy Blood DonorsPresenting in a Tertiary Care Hospital Blood Bank

IntroductionBlood transfusion is a critical component of modern healthcare, saving millions of lives globally every single year.Patients undergoing surgeries, trauma victims, cancer patients, and individuals with chronic conditions all rely on timely access to safe and compatible blood products.The success of medical interventions depends on a steady supply of blood, making blood donation a vital public health activity.Approximately 30% of the global population requires blood or its products at some point in their lives 1.Whether for emergency situations like natural disasters, accidents, war situations, major surgeries with high risk of blood loss, or chronic conditions like thalassemia, hemophilia and sickle cell anemia, chemotherapy and radiation therapy for cancer treatment, blood transfusions are a lifeline for 1,2 patients.In Pakistan, there are around 170 government and 450 private blood banks, with most of them attached to hospitals.Even in large cities, there is a significant blood shortage, with the supply falling short of more than half of the demand.However, many blood donations in Pakistan are made as replacements by family or friends, with only a small contribution from volunteer blood donors.The system is driven by