Trend of Pseudomonas aeruginosa antimicrobial susceptibility pattern from a rural North Indian healthcare setting

Abstract Background Pseudomonas aeruginosa is a gram negative opportunistic bacteria which causes infections in humans. The prevalence of antimicrobial resistance of P. aeruginosa makes it an infection difficult to treat by clinician. In this study we retrospectively analyzed antimicrobial susceptibility data of P. aeruginosa isolates from clinical samples from a period between January 2023 and September 2023 in Dhouj, Haryana. Methods 3860 clinical samples were processed and a total of 68 isolates identified phenotypically as P. aeruginosa were subjected to antimicrobial susceptibility testing by disk diffusion method. Results In our study, piperacillin-tazobactam showed the least resistance (2.9%) which is the mainstay for Pseudomonal infection and imipenem showed the highest resistance (58.8%). Conclusion This antimicrobial data of P. aeruginosa isolates gives an insight to its susceptibility pattern from a rural region in north India and will help the clinicians in treating patients and the need to strengthen the antibiotic policies in rural based healthcare delivery system and to minimize antibiotic misuse in rural areas to prevent spread of multi drug resistant P. aeruginosa .