Cobalt‐Catalyzed Green Alkylations of Anilines with Tetrahydrofurans
The use of bio-renewable resources as starting materials and reagents in synthetic chemistry is an important area for sustainable development. The use of tetrahydrofuran (THF) and 2-methyltetrahydrofuran (2-MeTHF) is reported, which can be obtained from lignocellulosic biomass, as potential alkylating agents for anilines. The developed N-alkylation process is catalyzed by the readily available cobalt salts and employs industrially available syngas as a reducing agent. The reported approach allows for the green and cost-effective production of N-alkylanilines from readily available feedstocks.
Authors
- Alexandra I. Balalaeva
- Matthias Beller (ORCID: https://orcid.org/0000-0001-5709-0965)
- Rajenahally V. Jagadeesh (ORCID: https://orcid.org/0000-0001-6079-0962)
- Oleg I. Afanasyev (ORCID: https://orcid.org/0000-0002-6224-6407)
- Zechen Wu
- Evgeniya Podyacheva (ORCID: https://orcid.org/0000-0002-0228-9261)
- Denis Chusov (ORCID: https://orcid.org/0000-0001-6770-5484)
Institutions
- National Research University Higher School of Economics (RU)
- VSB - Technical University of Ostrava (CZ)
- A. N. Nesmeyanov Institute of Organoelement Compounds (RU)
- Leibniz Institute for Catalysis (DE)
Publication Details
- Journal
- ChemSusChem
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1002/cssc.202402622
- Primary Topic
- Catalysis for Biomass Conversion
- Type
- article
- Field-Weighted Citation Impact
- 0.00