Biological Skin Substitutes in Pressure Ulcers: High-Purity Type I Collagen-Based Versus Amnion/Chorion Membrane

Helicoll<sup>®</sup> (HPTC) showed numerically superior healing rates, improved tissue regeneration parameters, required fewer reapplications with better structural stability of the healed wound, improved patient satisfaction outcomes compared to dHACM, suggesting potential clinical and economic advantages. These findings support the use of Helicoll<sup>®</sup> as an effective therapeutic option for PU management.

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Publication Details

Journal
Cureus
Published
2025-08-25
DOI
https://doi.org/10.7759/cureus.90956
Citations
4
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
4.10
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article

Biological Skin Substitutes in Pressure Ulcers: High-Purity Type I Collagen-Based Versus Amnion/Chorion Membrane

Naveen Narayan, Shivannaiah Chethan, Suhas Gowda, Yashas Hosur Ramegowda et al.
4 citations
Cureus
Wound Healing and Treatments
4.10
article

Biological Skin Substitutes in Pressure Ulcers: High-Purity Type I Collagen-Based Versus Amnion/Chorion Membrane

Naveen Narayan, Shivannaiah Chethan, Suhas Gowda, Yashas Hosur Ramegowda, Divakara S Raghupathi
article en
4 citations

Abstract

Helicoll<sup>®</sup> (HPTC) showed numerically superior healing rates, improved tissue regeneration parameters, required fewer reapplications with better structural stability of the healed wound, improved patient satisfaction outcomes compared to dHACM, suggesting potential clinical and economic advantages. These findings support the use of Helicoll<sup>®</sup> as an effective therapeutic option for PU management.

CureusVol. 17(8)
Institute of Medical Sciences (IN), Bangalore Medical College and Research Institute (IN)
Zero hunger
Openalex Percentile: Top 6%
Wound Healing and Treatments
4.10
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