Prediction of Sarcopenia Onset in Type 2 Diabetes Using Urinary Titin Levels: A Japanese Prospective Cohort Study
Elevated urinary titin levels predict sarcopenia and low muscle strength in individuals with type 2 diabetes, supporting its use as a noninvasive biomarker.
Authors
- Yoshinori Takiguchi
- Rie Tsutsumi (ORCID: https://orcid.org/0000-0001-6362-5823)
- Hiroshi Sakaue (ORCID: https://orcid.org/0000-0002-2468-2363)
- Kazuhiro Nomura (ORCID: https://orcid.org/0000-0002-2669-8289)
- Hayato Tanabe (ORCID: https://orcid.org/0000-0003-4576-8032)
- Kaori Shiroma
- Michio Shimabukuro (ORCID: https://orcid.org/0000-0001-7835-7665)
- Yuna Izumi-Mishima (ORCID: https://orcid.org/0009-0005-7503-2538)
- Mizusa Hyodo
- Masafumi Matsuo
Institutions
- Fukushima Medical University (JP)
- Kobe University (JP)
- Tokushima University (JP)
Publication Details
- Journal
- Diabetes Care
- Published
- 2025-08-25
- DOI
- https://doi.org/10.2337/dc25-1067
- Citations
- 2
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science