FOXP2 Mutations and the Dorsal Striatum: FOXP2’s Effect on Striatal Activity, Genetic Habit Formation, and Striatal Plasticity

Habit formation, or the transitioning of behaviors into habits, is a phenomenon that has been a point of interest for many studies in recent years. The striatum, a key hub of habit formation, has been at the center of habit-related research, with the current consensus portraying the striatum as a crucial point in transforming learning into routine habits. The FOXP2 gene, a gene once known for its association with language learning and speech mutations, were found to have a profound impact on the striatum’s ability to chunk and organize efficient habits. This review aims to put these various factors that contribute to striatal habit formation into conversation. We will also go over future possibilities regarding FOXP2 mutation application into drug addiction, as well as investigate potential reasons behind the effects of some FOXP2 mutations and the potentiation of habit formation.