Retrograde and Contralateral Metastasis of Clear Cell Renal Cell Carcinoma to the Spermatic Cord: A Case Report

Clear cell renal cell carcinoma (ccRCC) is known to display synchronous and metachronous metastases to a diverse set of organs. Retrograde and contralateral metastases of ccRCC are rare, with few cases in the literature. The mechanism of spread in these cases is thought to be facilitated by either the direct extension of tumor into the renal and gonadal veins or by the vertebral venous plexus. Here, we present a rare case of contralateral and retrograde ccRCC metastasis with extensive venous involvement.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-08-25
DOI
https://doi.org/10.7759/cureus.90970
Primary Topic
Renal cell carcinoma treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Retrograde and Contralateral Metastasis of Clear Cell Renal Cell Carcinoma to the Spermatic Cord: A Case Report

Joy M Hoang, Marcus Lee Quek, Maria M. Picken, Munira Charania
Cureus
Renal cell carcinoma treatment
article

Retrograde and Contralateral Metastasis of Clear Cell Renal Cell Carcinoma to the Spermatic Cord: A Case Report

Joy M Hoang, Marcus Lee Quek, Maria M. Picken, Munira Charania
article en

Abstract

Clear cell renal cell carcinoma (ccRCC) is known to display synchronous and metachronous metastases to a diverse set of organs. Retrograde and contralateral metastases of ccRCC are rare, with few cases in the literature. The mechanism of spread in these cases is thought to be facilitated by either the direct extension of tumor into the renal and gonadal veins or by the vertebral venous plexus. Here, we present a rare case of contralateral and retrograde ccRCC metastasis with extensive venous involvement.

CureusVol. 17(8)
Loyola University Medical Center (US)
Openalex Percentile: Top 67%
Renal cell carcinoma treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.