Serum S100A12 in the clinical diagnosis of sepsis-induced myocardial dysfunction: an integrated bioinformatics and clinical data analysis

As an inflammatory biomarker, S100A12 has independent predictive value, and its combination with cardiac enzymes enables the development of an efficient clinical warning model. The study highlights a potential new biomarker and treatment focus that could aid in early detection and management of sepsis-related cardiac injury.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-08-25
DOI
https://doi.org/10.3389/fcvm.2025.1640788
Citations
2
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
1.61
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article

Serum S100A12 in the clinical diagnosis of sepsis-induced myocardial dysfunction: an integrated bioinformatics and clinical data analysis

Fang Wu, Xiaoyan Wang, Ye Tian, H. Christian Hong
2 citations
Frontiers in Cardiovascular Medicine
S100 Proteins and Annexins
1.61
article

Serum S100A12 in the clinical diagnosis of sepsis-induced myocardial dysfunction: an integrated bioinformatics and clinical data analysis

Fang Wu, Xiaoyan Wang, Ye Tian, H. Christian Hong
article en
2 citations

Abstract

As an inflammatory biomarker, S100A12 has independent predictive value, and its combination with cardiac enzymes enables the development of an efficient clinical warning model. The study highlights a potential new biomarker and treatment focus that could aid in early detection and management of sepsis-related cardiac injury.

Frontiers in Cardiovascular MedicineVol. 12
The First People's Hospital of Guiyang (CN)
Openalex Percentile: Top 15%
S100 Proteins and Annexins
1.61
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