Predictive role of MGMT and IDH status in the efficacy of bevacizumab for high-grade glioma: a retrospective study
After controlling for potential confounding effects of chemotherapeutic agents, HGG patients with concurrent MGMT methylation and IDH mutations are likely to derive greater benefit from BEV treatment.
Authors
- Wenbin Ma (ORCID: https://orcid.org/0000-0003-4800-7992)
- Chao Wu (ORCID: https://orcid.org/0000-0002-6193-4398)
- Chengrui Yan (ORCID: https://orcid.org/0000-0003-4533-8905)
- Feng Ming (ORCID: https://orcid.org/0000-0001-7995-615X)
- Bai Xuexue
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Tengzhou Central People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3389/fonc.2025.1634892
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- Peking Union Medical College