Topical issues of standardization of <i>Rosa Cinnamomea</i> L. fruits and preparations

Aim – to study the amount of phenolic compounds in cinnamon rosehip fruits as part of optimizing approaches to the quantitative analysis of raw materials and preparations based on it. Material and methods. We studied the fruits of the cinnamon rosehip (Rosa cinnamomea L. fam. Rosaceae) harvested in the Samara region and the Republic of Mari El, as well as industrial samples of “Sirupus fructis Rosae” and “Cholosas” preparations, solutions of standard samples of gallus acid, ascorbic acid and catechin. The research methods involved direct spectrophotometry at 282 nm for quantitative determination of total flavonoids expressed as catechin equivalents and differential spectrophotometry at 412 nm expressed as rutin equivalents. Results. The analysis of the nature of absorption curves during direct spectrophotometry for extraction from cinnamon rosehip fruits and preparations based on them showed the presence of a manifested maximum at 276±2 nm, which is characteristic of catechin derivatives and gallic acid. The amount of reduced flavonoids expressed as catechin equivalents in fresh cinnamon rosehip fruits and in the preparations of “Sirupus fructis Rosae” and “Сholosas” based on them significantly exceeds the amount of oxidized flavonoids expressed as rutin equivalents. Conclusion. It seems most appropriate to conduct a quantitative analysis of cinnamon rosehip fruits, as well as preparations of “Sirupus fructis Rosae” and “Сholosas” derived from them, based on the amount of flavonoids expressed as catechin equivalents by direct spectrophotometry at 282 nm.