Reclassification of BRCA1 and BRCA2 Variants of Unknown Significance in a Turkish Cohort; A Single-Center, Retrospective Study
These results show that it may be possible to reclassify VUS, in this case <i>BRCA1/2</i> VUS, in light of changing genetic data. These results demonstrate the importance of VUS reclassification of <i>BRCA1/2</i> variants in clinical management, surgical decisions, risk counseling and screening.
Authors
- Leyla Özer (ORCID: https://orcid.org/0000-0001-8763-5268)
- Süleyman Aktuna (ORCID: https://orcid.org/0000-0003-0348-3530)
- Evrim Ünsal (ORCID: https://orcid.org/0000-0002-3965-7347)
Institutions
- Yüksek İhtisas Üniversitesi (TR)
- Intergen (Turkey) (TR)
Publication Details
- Journal
- European Journal of Breast Health
- Published
- 2025-08-25
- DOI
- https://doi.org/10.4274/ejbh.galenos.2025.2025-5-2
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00