Protective effect of N-acetylcysteine in doxorubicin-induced primary ovarian failure in female rats
NAC preserved ovarian reserve and follicular integrity by suppressing oxidative stress, inflammation, and apoptosis induced by DOX. These findings highlight NAC as a promising protective agent against chemotherapy-induced ovarian toxicity.
Authors
- İhsan Karaboğa (ORCID: https://orcid.org/0000-0001-6708-1229)
- Mehmet Doğan (ORCID: https://orcid.org/0000-0001-8806-0400)
- Mehmet Öz (ORCID: https://orcid.org/0000-0003-4167-2623)
- Hüseyin Erdal (ORCID: https://orcid.org/0000-0003-0786-5077)
Institutions
- Aksaray University (TR)
- Tekirdağ Namık Kemal University (TR)
- Department of Embryology (US)
- Istanbul Memorial Hospital (TR)
Publication Details
- Journal
- Journal of Turkish Society of Obstetric and Gynecology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.4274/tjod.galenos.2025.71654
- Primary Topic
- Garlic and Onion Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00