Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington’s disease models

This study suggests that impaired CB1R function in hippocampal GABAergic interneurons contributes to memory dysfunction in HD.

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Publication Details

Journal
Translational Neurodegeneration
Published
2025-08-25
DOI
https://doi.org/10.1186/s40035-025-00500-w
Citations
1
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.91

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article

Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington’s disease models

Anna Vázquez‐Oliver, Laura Molina‐Porcel, Gertrudis Perea, Iker Bengoetxea de Tena et al.
1 citations
Translational Neurodegeneration
Genetic Neurodegenerative Diseases
0.91
article

Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington’s disease models

Anna Vázquez‐Oliver, Laura Molina‐Porcel, Gertrudis Perea, Iker Bengoetxea de Tena, Carlos Costas‐Insua, Candela González-Arias, Nadia Di Franco, Sílvia Ginés, Andrea Sánchez-Ruiz, Manuel Guzmán, Rafael Rodríguez‐Puertas, Analı́a Bortolozzi, Andrés Ozaita, Lluis Maria Miquel Rio, Ferran Enfedaque, Alba Pereda-Velarde
article en
1 citations

Abstract

This study suggests that impaired CB1R function in hippocampal GABAergic interneurons contributes to memory dysfunction in HD.

Translational NeurodegenerationVol. 14(1)
Consejo Superior de Investigaciones Científicas (ES), University of the Basque Country (ES), Universitat Pompeu Fabra (ES), Instituto Cajal (ES), Instituto de Salud Carlos III (ES), Hospital de Sant Pau (ES), Biomedical Research Networking Center on Neurodegenerative Diseases (ES), BioCruces Health research Institute (ES), Centro de Investigación Biomédica en Red de Salud Mental (ES), Departament de Salut (ES), Centro de Investigación Biomédica en Red (ES), Hospital Clínic de Barcelona (ES), Institut d'Investigacions Biomèdiques de Barcelona (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Fundació Clínic per a la Recerca Biomèdica (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
Fundació la Marató de TV3, Ministerio de Ciencia, Innovación y Universidades, Generalitat de Catalunya, Eusko Jaurlaritza, Ministerio de Ciencia e Innovación, Universitat de Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Agència de Gestió d'Ajuts Universitaris i de Recerca, Agencia Estatal de Investigación
Openalex Percentile: Top 23%
Genetic Neurodegenerative Diseases
0.91
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