LC-MS/MS method for co-estimation of doxorubicin and piperine: formulation development and pharmacokinetic studies
The findings highlight the potential of SLN-based co-delivery of DOX and PIP for oral metronomic chemotherapy. The validated LC-MS/MS method ensures precise pharmacokinetic assessment, which is crucial for future clinical translation. This study provides a promising strategy for enhancing oral chemotherapy efficacy.
Authors
- Manish K. Chourasia (ORCID: https://orcid.org/0000-0002-8318-9325)
- Amit Kumar Kashyap (ORCID: https://orcid.org/0000-0002-2716-8482)
- Jiaur R. Gayen (ORCID: https://orcid.org/0000-0001-7703-9307)
- Divya Chauhan (ORCID: https://orcid.org/0009-0001-8883-1719)
- Pooja Yadav (ORCID: https://orcid.org/0000-0002-5914-563X)
- Pavan Kumar Yadav (ORCID: https://orcid.org/0000-0002-1847-7486)
Institutions
- Central Drug Research Institute (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1080/17576180.2025.2548198
- Citations
- 1
- Primary Topic
- Piperaceae Chemical and Biological Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.56