Comparison of ultrasonographic (SonoVue) and radiographic (Imeron) contrast agents for intralesional application in the head and neck area: An in vitro study

SonoVue provided a significant contrast effect for distinguishing the lesion from the surrounding soft tissue at dilutions of 1/10 and 1/20. Imeron300 showed a slightly superior contrast effect, even at dilutions of 1/50 and 1/100. However, CEUS using SonoVue in low dilutions seemed suitable for intralesional application in vitro. Further in vivo studies are required to validate the current results and determine the optimal contrast-agent concentration.

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Publication Details

Journal
Ultrasound
Published
2025-08-25
DOI
https://doi.org/10.1177/1742271x251365429
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Comparison of ultrasonographic (SonoVue) and radiographic (Imeron) contrast agents for intralesional application in the head and neck area: An in vitro study

Philipp Jehn, Fritjof Lentge, Stephan Alexander Bettag, Michael Neuhaus et al.
Ultrasound
Salivary Gland Tumors Diagnosis and Treatment
article

Comparison of ultrasonographic (SonoVue) and radiographic (Imeron) contrast agents for intralesional application in the head and neck area: An in vitro study

Philipp Jehn, Fritjof Lentge, Stephan Alexander Bettag, Michael Neuhaus, Nils‐Claudius Gellrich, Philippe Korn, Max Lukas Linderkamp
article en

Abstract

SonoVue provided a significant contrast effect for distinguishing the lesion from the surrounding soft tissue at dilutions of 1/10 and 1/20. Imeron300 showed a slightly superior contrast effect, even at dilutions of 1/50 and 1/100. However, CEUS using SonoVue in low dilutions seemed suitable for intralesional application in vitro. Further in vivo studies are required to validate the current results and determine the optimal contrast-agent concentration.

Ultrasound
Medizinische Hochschule Hannover (DE)
Openalex Percentile: Top 64%
Salivary Gland Tumors Diagnosis and Treatment
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