Genetic-environmental Risk Factors for Tooth Agenesis: A Familial Case-control Study in China
Genetic contribution is more statistically significant in TA patients with more severe phenotypes, and in females. Heritability of TA declined with increased environmental exposure. Multiple genetic modes exist in TA families. Additionally, environmental factors, like unprotected electromagnetic radiation during pregnancy, are likley to play a role in TA development.
Authors
- Xinyue Guo (ORCID: https://orcid.org/0000-0003-4151-1678)
- Xiaohong Duan (ORCID: https://orcid.org/0000-0002-6747-1734)
- Taoyun Xu
Institutions
- Air Force Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1016/j.identj.2025.100956
- Citations
- 1
- Primary Topic
- dental development and anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.81