Safety and Efficacy Findings From a Phase Ib/ <scp>II</scp> Study of <scp>ASP</scp> ‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
ASP-1929 photoimmunotherapy plus pembrolizumab was generally tolerable, with promising efficacy in patients with recurrent/metastatic HNSCC.
Authors
- Ann M. Gillenwater (ORCID: https://orcid.org/0000-0002-0935-0037)
- Michael K. Gibson (ORCID: https://orcid.org/0000-0002-1500-9281)
- Coral Olazagasti (ORCID: https://orcid.org/0000-0002-6658-0170)
- Kathryn M. Van Abel (ORCID: https://orcid.org/0000-0003-0513-4203)
- Joseph Curry (ORCID: https://orcid.org/0000-0001-9507-4237)
- Shirley Y. Su (ORCID: https://orcid.org/0000-0002-3903-8204)
- R. Bryan Bell
- Susanne M. Arnold (ORCID: https://orcid.org/0000-0001-6542-9551)
- Michael C. Kwon (ORCID: https://orcid.org/0000-0002-1661-2971)
- Katharine A. Price (ORCID: https://orcid.org/0000-0002-5738-1866)
- Francisco Civantos (ORCID: https://orcid.org/0000-0002-1648-0868)
- Joseph Valentino
- Amy Haseley Thorne
- Kyle Mannion (ORCID: https://orcid.org/0000-0001-9391-1791)
- Jennifer M. Johnson (ORCID: https://orcid.org/0000-0003-4548-307X)
- David M. Cognetti (ORCID: https://orcid.org/0000-0001-7039-3055)
- Toshiaki Suzuki (ORCID: https://orcid.org/0000-0002-0650-6251)
- Haiying Dong
Institutions
- Rakuten (Japan) (JP)
- Mayo Clinic (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Kentucky (US)
- University of Miami (US)
- Thomas Jefferson University (US)
- Providence Portland Medical Center (US)
- Lexington VA Health Care System (US)
- WinnMed (US)
- Sidney Kimmel Cancer Center (US)
- EP Analytics (United States) (US)
- Mayo Clinic in Arizona (US)
- Rakuten (United States) (US)
- Mayo Clinic in Florida (US)
- Sylvester Comprehensive Cancer Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1002/hed.70014
- Citations
- 7
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 7.32
Funders
- Rakuten Medical