Cytokine levels in immediate loaded and unloaded mini-screw: A split-mouth randomised clinical trial

Although all biomarker levels were statistically higher in the immediately loaded group at all experimental time points in comparison with the unloaded group, no mini-screws were lost. This suggests a balanced and normal adaptive bone response to the mechanical stress of immediate loading, with no negative impact on clinical outcomes.

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Publication Details

Journal
Journal of Orthodontics
Published
2025-08-25
DOI
https://doi.org/10.1177/14653125251358815
Primary Topic
Orthodontics and Dentofacial Orthopedics
Type
article
Field-Weighted Citation Impact
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article

Cytokine levels in immediate loaded and unloaded mini-screw: A split-mouth randomised clinical trial

M Mendes, Amanda Cunha Regal de Castro, Caio Luiz Bitencourt Reis, Gabriela Leite Pedroso et al.
Journal of Orthodontics
Orthodontics and Dentofacial Orthopedics
article

Cytokine levels in immediate loaded and unloaded mini-screw: A split-mouth randomised clinical trial

M Mendes, Amanda Cunha Regal de Castro, Caio Luiz Bitencourt Reis, Gabriela Leite Pedroso, Paôla Caroline da Silva Mira, Maria Bernadete Sasso Stuani
article en

Abstract

Although all biomarker levels were statistically higher in the immediately loaded group at all experimental time points in comparison with the unloaded group, no mini-screws were lost. This suggests a balanced and normal adaptive bone response to the mechanical stress of immediate loading, with no negative impact on clinical outcomes.

Journal of OrthodonticsVol. 52(3)
Universidade Federal do Rio de Janeiro (BR), Universidade de Ribeirão Preto (BR), Universidade de São Paulo (BR)
Openalex Percentile: Top 77%
Orthodontics and Dentofacial Orthopedics
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Cytokine levels in immediate loaded and unloaded mini-screw: A split-mouth randomised clinical trial — M Mendes, Amanda Cunha Regal de Castro, et al. · Journal of Orthodontics (2025) | TGRS Research Map | TGRS