Ameliorative effects of Brassica oleracea var. viridis ethanol extract and fractions on cimetidine-induced reproductive toxicity in male Wistar rats
<i>Brassica oleracea</i> var. <i>viridis</i> exhibits significant protective effects against cimetidine-induced reproductive toxicity through hormonal regulation, antioxidative mechanisms, and tissue preservation. The ethanol extract of <i>Brassica oleracea</i> (ELEBO) showed the most potent activity, supporting its potential use as a therapeutic adjunct in male infertility linked to pharmaceutical exposures.
Authors
- Daniel Udofia Owu (ORCID: https://orcid.org/0000-0002-8264-9131)
- Felix Nnaemeka Ugwu
- Olufunke Onaadepo
- Victor Otu Oka (ORCID: https://orcid.org/0000-0001-7230-6293)
- Patrick Maduabuchi Aja (ORCID: https://orcid.org/0009-0006-2450-9460)
- Emmanuel Orire Ikuomola
Institutions
- Kampala International University (UG)
- Kampala International University in Tanzania (TZ)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-08-25
- DOI
- https://doi.org/10.3389/fvets.2025.1645967
- Citations
- 2
- Primary Topic
- Nigella sativa pharmacological applications
- Type
- article
- Field-Weighted Citation Impact
- 4.76